Vol. 55 No. sp. is. 1 (2023): Vol. 55, special issue 1, 2023: In memoriam to the late Prof. Dr. Yusuf YAĞCI (1952-2023)
ITU ARI-A Natural Sciences

The Role of Glucose Oxidase in Free Radical Polymerization

Elif L. Sahkulubey Kahveci
Beykent University, Faculty of Engineering and Architecture, Department of Biomedical Engineering, Sariyer, Istanbul, Türkiye
Muhammet Ubeydullah Kahveci
Istanbul Technical University

Published 04/30/2024


  • Free radical polymerization,
  • oxygen inhibition,
  • enzyme

How to Cite

Sahkulubey Kahveci, Elif L., and Muhammet Ubeydullah Kahveci. 2024. “The Role of Glucose Oxidase in Free Radical Polymerization”. ITU ARI Bulletin of Istanbul Technical University 55 (sp. is. 1):57-62. https://ari.itu.edu.tr/index.php/ituari/article/view/79.


Enzymes are biological catalyst that are essential for living organisms. Enzymes have been extensively employed in many industrial applications including medicine, cosmetics, pharmaceutics, dairy, bakering, beverage, animal feed, paper, leather, and etc. In addition, enzymes have been widely utilized in polymer industry and chemistry. Herein, roles of the enzymes in free radical polymerization are reviewed. Enzymes are usually utilized in free radical polymerization for deoxygenation of polymerization medium or generation of free radicals in a cascade reaction. One of the primary challenges in radical polymerization revolves around oxygen inhibition. Various strategies have been devised to address this issue. These include employing inert gases, applying coatings, increasing initiator concentration, incorporating additives such as amines, thiols, boranes, and silanes, as well as utilizing enzymes for deoxygenation. Prof. Yagci significantly advanced this field with groundbreaking research. Yagci and colleagues introduced a pioneering photopolymerization system that utilized glucose oxidase (GOx) and sugar to eliminate oxygen from the polymerization environment. This innovative approach served as inspiration for others to develop controlled/living polymerization techniques utilizing enzyme-mediated deoxygenation.


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