https://ari.itu.edu.tr/index.php/ituari/issue/feed ITU ARI Bulletin of Istanbul Technical University 2024-02-06T16:49:04+03:00 Ahmet GÜL ahmetg@itu.edu.tr Open Journal Systems <p>ARI – Bulletin of the Istanbul Technical University publishes:</p> <p>- Original research articles and short communications describing recent discoveries and developments in related fields.<br />- Review papers, dealing with emerging areas of basic, applied, natural sciences and engineering research.<br />- Special issues with guest editor(s) dedicated to relevant fundamental topics and to eminent scholars.</p> <p>All submitted articles will be peer reviewed based on anonymous refereeing.</p> <p>ARI – Bulletin of the Istanbul Technical University welcomes manuscripts spanning below fields of study, however, authors are encouraged to suggest relevant topics which might also be considered for a publication in the journal.</p> <p>| Basic Sciences | Physical Sciences | Engineering Sciences | Natural Sciences |</p> https://ari.itu.edu.tr/index.php/ituari/article/view/78 GİRİŞ 2024-02-06T16:49:04+03:00 Barbaros AKKURT akkurtb@itu.edu.tr <p>2023 senesi İTÜ’ye iyi gelmedi. Önce Yusuf, arkadan Aral gitti ve her ikisi de İTÜ’nün akademik performansında büyük iki delik bıraktılar. Yusuf benim iyi bir dostum, bazen da dert ortağımdı. Derdimiz ise Türkiye’nin bilim dünyasındaki yeriydi. Yusuf üstün başarılı bir kimyacıydı ve en son konuştuğumuzda ona Nobel getirebilecek projelerini anlatmıştı. Ben de ona eğer Nobel alırsa, İTÜ kampüsünün ortasına çıkıp zevkten göbek atacağımı söylemiştim. Ne yazık ki ölümü buna izin vermedi.</p> <p>&nbsp;</p> <p>Yusuf’la bilimsel ilgilerimiz birbirlerinden epey farklı olduğu için bir araya geldiğimizde oradan buradan sohbet ederdik, Türkiye’nin bilimdeki geriliğinden de dem vurup üzüntülerimizi paylaşırdık. Ama Yusuf asla kötümser değildi. Müthiş zekâsı ve hazırcevaplığı, nüktedanlığına ayrı bir lezzet katardı. Ben Yusuf’u hiç asık yüzlü görmemiştim. Ama ölümü hepimizin yüzünü astı, en azından ben hâlâ yüzümü eski haline getiremiyorum. Onun esprilerini, hınzır sataşmalarını düşünüyorum gülebilmek için, ama onları yapan ortada olmayınca yüzüm eski haline gelmeyi reddediyor. Şimdi Yusuf’un arkada bıraktıklarına düşen en önemli görev onun başlattığı ivmeyi hızlandırarak sürdürmek ve onun almasını hepimizin çok istediği kimya Nobel ödülünü üniversitemize getirmek.</p> <p>&nbsp;</p> <p>O zaman da İTÜ belki dünya çapında arzu edilen bir “Yusuf Yağcı Kimya Madalyasını” hayata geçirir, bizden sonraki nesiller Yusuf’un o her zaman gülümseyen, dost yüzünü bir altın yüzeyde görüp heyecanlarına heyecan katabilirler.</p> <p>&nbsp;</p> <p>Yusuf öldü. Ama onun eserinin, onun azîz hâtırasının ilelebet yaşamasını temin etmek artık arkada bıraktığı bizlerin borcudur. Nur içinde yat azîz arkadaşım. Senin saçtığın ışıklar hepimizin sanki daha da pırıltılı görülmemizi sağlıyor bu çeyrek bin yıllık üniversitemizde. İnan, sen kalbimizde her zaman var olacaksın, anılarınla İTÜ’ye nur yağdırmaya devam edeceksin.</p> 2024-02-06T00:00:00+03:00 Copyright (c) 2024 Barbaros AKKURT https://ari.itu.edu.tr/index.php/ituari/article/view/71 Hyaluronic Acid-Enriched Pectin-Based Hydrogel Films for Wound Healing 2024-01-03T10:10:03+03:00 Ö. Zeynep Güner Yılmaz yilmaz.zeynep@itu.edu.tr F. Seniha Güner guners@itu.edu.tr <p>Wound healing research is always looking for approaches to improve patient care. Advanced wound dressings are critical in this process. In this context, the article focuses on the comprehensive examination of the potential of hyaluronic acid-enriched pectin-based hydrogel films to advance wound healing. For comparative analysis, two formulations were prepared: a pectin matrix and a film containing fifty percent hyaluronic acid and pectin. Both formulations were cross-linked using calcium ions. The hydrogels underwent thorough characterization, including Fourier-transform infrared spectroscopy analysis for chemical composition, differential scanning calorimetry for thermal properties determination, and scanning electron microscope imaging for morphological examination of cross-sections. We thoroughly examine their fluid-handling capacities, dehydration rates, and water vapor permeability through meticulous inspection. These characteristics have a significant impact on elasticity, moisture retention, and overall effectiveness throughout the healing process. To demonstrate the transformative potential of HA-enriched pectin-based hydrogel films, we compare their properties to those of pectin hydrogel and a commercial alginate-based wound dressing. As a result, the investigation revealed a notable enhancement in the transparency of the wound dressing, a crucial factor for facilitating continuous monitoring of the wound site without necessitating frequent removal of the dressing. The improvement in water vapor permeability suggests an optimized moisture balance, fostering an environment conducive to efficient wound healing. Moreover, the smoother film contributes to the overall comfort for patients and potentially minimizes skin irritation and discomfort during prolonged wear. The innovative features identified in this study collectively point towards the prospect of these hydrogel films not only as effective wound dressings but also as a step forward in addressing the practical aspects of patient comfort and convenience.</p> 2024-02-03T00:00:00+03:00 Copyright (c) 2024 F. Seniha Güner, Ö. Zeynep Güner Yılmaz https://ari.itu.edu.tr/index.php/ituari/article/view/72 Visible Light-Induced Fabrication of a Clickable Cu(I) Benzophenone Dicarboxylate Polymer - Polyacrylamide Hydrogel Composite 2024-01-29T20:06:12+03:00 Sena Ermiş ermiss23@itu.edu.tr Mehmet Bilgehan Bilgiç mehmet@kubilayboya.com Barış Kışkan kiskanb@itu.edu.tr Kerem Kaya kkaya@itu.edu.tr <p>Hydrogels are a class of hydrophilic polymers that have been widely applied in numerous fields, most of which are related to bioengineering such as tissue scaffolds, biosensing and antibacterial activity. Especially, polyacrylamide (PAAm) hydrogels, due to their superior stability, non-toxicity and viscoelasticity, have been extensively studied over the last two decades in different bio-related applications. Coordination polymers (CPs) including metal-organic frameworks (MOFs), due to tunability of the organic linkers and metal ions, and their robustness, have been incorporated with hydrogels in order to improve the physical/chemical properties of the final composite. Herein, we report for the first time, the use of a photoactive Cu(I) coordination polymer, as Norrish type II photoinitiator, for the visible light-induced <em>in situ</em> fabrication of a clickable and highly-crosslinked Cu(I)CP-PAAm hydrogel composite using water as the solvent. Due to the high stability of the Cu(I)CP in water, that was demonstrated by powder X-ray studies, the release of copper ions was observed to occur after more than two days. Another advantage of the developed synthetic method, is the possibility to readily post-modify the hydrogel-composite by employing an azide-functionalized polymer through internal copper-catalyzed azide-alkyne click reaction.</p> 2024-02-03T00:00:00+03:00 Copyright (c) 2024 Sena Ermiş, Mehmet Bilgehan Bilgiç, Barış Kışkan, Kerem Kaya https://ari.itu.edu.tr/index.php/ituari/article/view/74 Strecker 3-Component Reaction for Post-Polymerization Modification of Pendant Aldehyde Functional Polymers 2024-01-03T10:26:49+03:00 Mine Aybike Ersin aybike.ersin@gmail.com Emre Akar akare20@itu.edu.tr Dilhan Kandemir dkandemiir@gmail.com Serter Luleburgaz luleburgaz@itu.edu.tr Volkan Kumbaraci kumbaracii@itu.edu.tr Ufuk Saim Gunay gunayuf@itu.edu.tr Hakan Durmaz durmazh@itu.edu.tr <p>Aldehydes have always been useful building blocks in organic chemistry due to their high and diverse reactivity. They also offer easy access to various other functionalities and allow reactions to be performed under mild conditions. This distinguished versatility has allowed aldehyde-bearing polymers to be a good platform for post-polymerization modification reactions to prepare functional polymers. This study exploited the Strecker 3-component reaction to obtain polymers with α-aminonitrile groups at the side chain for the first time. For this purpose, firstly, an aldehyde-functional polymer was synthesized from 4-formylphenyl methacrylate through free radical polymerization and then modified with amine compounds in the presence of trimethylsilyl cyanide and a catalytic amount of <em>p</em>-toluenesulfonic acid at room temperature. The spectroscopic analyses confirmed the successful synthesis of corresponding α-aminonitriles.</p> 2024-02-13T00:00:00+03:00 Copyright (c) 2024 Mine Aybike Ersin, Emre Akar, Dilhan Kandemir, Serter Luleburgaz, Volkan Kumbaraci, Ufuk Saim Gunay, Hakan Durmaz https://ari.itu.edu.tr/index.php/ituari/article/view/73 Perspectives on the Curing of Benzoxazine Resins 2024-01-04T09:08:13+03:00 Barış Kışkan kiskanb@itu.edu.tr Füsun Şeyma Güngör gungorfus@itu.edu.tr <p>Benzoxazines are a class of heterocyclic compounds that can be polymerized to form polybenzoxazines, which have excellent properties such as thermal stability, flame retardance, low shrinkage, and chemical resistance. The curing of benzoxazines involves a thermal cationic ring-opening polymerization, which can be influenced by various factors such as catalysts, co-monomers, temperature, and time. In general, the curing temperatures of benzoxazines are considered as high and lie between 180 ⁰C and 260 ⁰C depending on the monomer structure. This nature of benzoxazine resins could limit their wider applications in different areas. Therefore, lowering the curing temperatures could play a critical role in the benzoxazine resin chemistry. This review summarizes the recent advances in the understanding of the curing mechanisms of benzoxazine resins, with a focus on the factors influencing the curing kinetics and the resulting material properties.</p> 2024-02-24T00:00:00+03:00 Copyright (c) 2024 Barış Kışkan, Füsun Şeyma Güngör